Biden appeals for tougher gun laws: ‘How much more carnage?’ – By ZEKE MILLER and WILL WEISSERT June 2, 2022

WASHINGTON (AP) — “Enough, enough,” President Joe Biden exclaimed over and over Thursday night, as he delivered an impassioned address to the nation …

Biden appeals for tougher gun laws: ‘How much more carnage?’ – By ZEKE MILLER and WILL WEISSERT June 2, 2022

Spanish Sundays, finishing Masot’s Coming of Age series, and Health via Community

Inspiring Critical Thinking and Community via Books, Lessons, and Story

–I continue to insist on the importance, for health, of inclusion in the community.

El sepulcro del cuervo by Núria Masot
 

To think, to dare, and to love. Absolutely inspiring. This last book of Masot’s quintology is as good as the Very Good first (La Sombra del Templario), nearly as good as the Extremely Good second book (Laberinto: El Laberinto de la Serpiente) of this series. More inter-generational than Harry Potter(Harry Potter and the Sorcerer’s Stone), and using the test of war (though battle scenes are almost never seen) as the coming of age ritual for both young men who come of age in the series, there remains a paradox. The teacher Bernard, who dies in the very start of book 1, remains a constant presence throughout the series. He is the real hero.

ShiraDest
28 August, 12015 HE
Bretagne

 

So, it turns…

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El Sepulcro del Cuervo, por/by Núria Masot, & La Empatia/Empathy

Inspiring Critical Thinking and Community via Books, Lessons, and Story

El sepulcro del cuervoEl sepulcro del cuervo: Núria Masot

(the English review is here…)

La empatîa lleve a todo: Pensar, atreverse y amar. Absolutamente inspirador. Este ultimo libro de la quintologia de Masot està tan buena como el Muy Buen (La Sombra del Templario) primer libro, y casi casi tanto como el Buenisimo segundo (el Laberinto: El Laberinto de la Serpiente) de este serie. Se involucran màs los viejos con los jovenes que en el serie de Harry Potter (Harry Potter and the Sorcerer’s Stone), y se usa la guerra como preuba de maturidad para los dos jovenes hecho hombres en el serie. Pero queda un paradoxo. El maestro Bernard, quien muere al comienzas del libro 1, se queda como una presencia constante en todo los libros. Es el verdadero protagonista.

Shira “Era Holocena/Humana” Destinie
28 Augosto del año 12 015 EH

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Click here to read, if you like:

B5,La…

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Caminho

Vivaldi translation: “The transformation you want so much, depends solely and exclusively on you. No path can be taken first, if not (inside) from within. The physical only exists, if before, the change begins internally. One step taken is a road that opens towards a new horizon. ”

Marii Freire Pereira

Pensamentos.me/VEM comigo!

“A transformação que você tanto deseja, depende única e exclusivamente de você. Nenhum caminho pode ser percorrido primeiro, se não ( for) por dentro. O físico só existe, se antes, a mudança começar internamente. Um passo dado, é uma estrada que se abre rumo a um novo horizonte. “

Marii Freire Pereira

https://Pensamentos.me/VEM comigo!

Imagem: pinterest/ Twitter

Santarém, Pá 2 de junho de 2022

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Frontiers | Inhalational monkeypox virus infection in cynomolgus macaques | Cellular and Infection Microbiology

…When developing an animal model, it is important that the experimental route of infection be the same or similar to the anticipated route of infection in human disease. Transmission of smallpox occurs from aerosols from close contact with an infected individual. These infectious droplets can implant onto the nasal, oral, or pharyngeal mucous membranes or in the alveolar space of the lung and cause disease (Fenner et al., 1988)…

…The intratracheal method of exposing cynomolgus macaques to MPXV was recently described (Stittelaar et al., 2006Goff et al., 2011). This approach attached a microsprayer to a bronchoscope for intratracheal infection. Kramski infected marmosets with cowpox virus that had been isolated from a lethal orthopox virus outbreak in New World monkeys, termed calpox. Calpox was lethal not only via the intravenous route but also by the intranasal route, and the marmosets reproducibly develop symptoms resembling smallpox in humans (Kramski et al., 2010). Small particle aerosols containing MPXV have been used to infect the lower respiratory tracts of cynomolgus macaques (Zaucha et al., 2001Nalca et al., 2010) via an inhalational route. These studies were able to replicate the severe symptoms observed in intravenous infections, but required specialized equipment to generate aerosols containing MPXV…

…Multiple objectives were fulfilled from these tests. An aerosol exposure system was characterized using aerosolized MPXV, and it was shown that gelatin filters and impingers of type model 7541 generated equivalent enumeration results when sampling the MPXV aerosol. Following characterization of the aerosol exposure system, an NHP inhalation study determined a lethal exposure dose of MPXV, and an inhalation cynomolgus macaque model of MPXV infection was developed. Actual NHP exposures were performed with high precision relative to target dose, and the lesions and lethality were similar to the previously published data for the cynomolgus monkey (Zaucha et al., 2001Nalca et al., 2010)…

 

Source: Frontiers | Inhalational monkeypox virus infection in cynomolgus macaques | Cellular and Infection Microbiology