Although scientists around the world are searching very hard, the origins of SARS-CoV-2 remain elusive. In fact, for many infectious pathogens, although their origins have been traced back decades, the debate around the origins remains alive.
discovered a human serum sample collected in Léopoldville (now Kinshasa, Democratic Republic of the Congo) in early 1959 that suggested exposure to HIV. Phylogenetic analysis subsequently suggested that an HIV ancestor had been introduced to Africa before 1959,
and a relatively recent report, from 2008, revealed that the HIV-1 M group originated in about 1908 (CI 1884–1924) and has been circulating in the population for about 100 years.