SARS-CoV-2 Transmission From People Without COVID-19 Symptoms | Infectious Diseases | JAMA Network Open | JAMA Network

The findings presented here complement an earlier assessment21 and reinforce the importance of asymptomatic transmission: across a range of plausible scenarios, at least 50% of transmission was estimated to have occurred from persons without symptoms. This overall proportion of transmission from presymptomatic and never symptomatic individuals is key to identifying mitigation measures that may be able to control SARS-CoV-2. For example, if the reproduction number (R) in a given setting is 2.0, then at least a 50% reduction in transmission is needed to drive the reproductive number below 1.0. Given that in some settings R is likely much greater than 2 and more than half of transmissions may come from individuals who are asymptomatic at the time of transmission, effective control must mitigate transmission risk from people without symptoms. Source: SARS-CoV-2 Transmission From People Without COVID-19 Symptoms | Infectious Diseases | JAMA Network Open | JAMA Network