Goethe-Universität — COVID-19 research: Anti-viral strategy with double effect

Professor Ivan Đikić, Director of the Institute of Biochemistry II at University Hospital Frankfurt and last author of the paper, explains: “We used the compound GRL-0617, a non-covalent inhibitor of PLpro, and examined its mode of action very closely in terms of biochemistry, structure and function. We concluded that inhibiting PLpro is a very promising double-hit therapeutic strategy against COVID-19. The further development of PLpro-inhibiting substance classes for use in clinical trials is now a key challenge for this therapeutic approach.”

Source: Goethe-Universität — COVID-19 research: Anti-viral strategy with double effect

Complaining about wearing a mask because of coronavirus? These nurses don’t want to hear it – ABC News Australia

A woman wears a surgical cap and gown and has tape across her nose.

“We have pressure injuries on our forehead and bruising on our chins and our noses.

“Seeing people in the community complain about their masks that they have to wear for half an hour to go to the shops is a little bit disheartening when our masks actually cause us physical injuries, just to keep us and our patients safe.”

 

Source: Complaining about wearing a mask because of coronavirus? These nurses don’t want to hear it – ABC News

‘They need voters’: QAnon is finding a home in the Republican party

Believers of the conspiracy theory, labelled a potential domestic terror threat by the FBI, are running for national office as Republican candidates

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Believers of the conspiracy theory, labelled a potential domestic terror threat by the FBI, are running for national office as Republican candidates

According to one congressional candidate for America’s House of Representatives, Covid-19 and the Black Lives Matter movement are a screen “for pedophilia and human trafficking”.

Another has claimed the US has a “once-in-a-lifetime opportunity to take this global cabal of Satan-worshiping pedophiles out”, while several others running for national office have posted cryptic memes hinting at a powerful global elite that must be abolished.

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Duterte says sorry, restores quarantine restrictions around Manila as cases soar, SE Asia News & Top Stories – The Straits Times

President Rodrigo Duterte late on Sunday (Aug 2) restored stricter quarantine restrictions around Metropolitan Manila after the Philippines tallied four straight days of record increases in coronavirus infections, and health workers warned of a collapse of the healthcare system. “The cry of the moment… is well taken, and they are right, the health workers… We agree that you are bone-weary, both from the pressure and also the uncertainty and fear of getting Covid and not having anything in return,” Mr Duterte said in a late-evening broadcast after meeting with his ministers.

Source: Duterte says sorry, restores quarantine restrictions around Manila as cases soar, SE Asia News & Top Stories – The Straits Times

Couple arrested after yelling ‘white power’, using Nazi salute – The Jerusalem Post

The victims filed a hate crime/vandalism report with police the following day, July 23, and on July 24, police had obtained arrest warrants for both of the suspects.

A California couple has been arrested on hate crime and vandalism charges after they were seen in a widely shared video spouting off white supremacist rhetoric in the direction of a Black man and his girlfriend, according to the Torrance Police Department.

The suspects, Gregory Howell of Carson and Rachel Howell of Seal Beach, were videotaped on July 22 approaching the Black man and his girlfriend at a red light in Torrance after stopping their truck in front of the victims’ car.

Source: Couple arrested after yelling ‘white power’, using Nazi salute – The Jerusalem Post